Medium-chain triglyceridesthiab lub zog metabolism. Fatty acids yog cais raws li qhov ntev ntawm lawv cov qauv carbon: luv-chain fatty acids (tsawg dua los yog sib npaug li 5 carbons), nruab nrab-chain fatty acids (6-12 carbons), thiab ntev-chain fatty acids ( Ntau dua lossis sib npaug li 14 carbons). Lawv tuaj yeem raug cais raws li saturated fatty acids, monounsaturated fatty acids, thiab polyunsaturated fatty acids nyob ntawm seb muaj thiab pes tsawg ntawm unsaturated bonds nyob rau hauv lawv cov carbon saw qauv.
Long-chain fatty acids nrog carbon atoms ntau dua 12 yog qhov tseem ceeb ntawm kev noj zaub mov kom tsawg, thaum nruab nrab-chain fatty acids nrog carbon atoms ntawm 6 thiab 12 yog noj me me. Medium-chain fatty acids sib txawv ntawm cov saw ntev fatty acids nyob rau hauv cov nqe lus ntawm lub cev muaj zog, digestion thiab nqus, thiab metabolism hauv lub cev.
Medium-chain fatty acids (MCFA) yog fatty acids uas muaj li ntawm 6-12 carbon atoms uas tsis tshua muaj nyob rau hauv cov xwm. Lawv feem ntau yog muab los ntawm cov khoom siv xws li txiv maj phaub roj, txiv maj phaub roj, cov khoom noj siv mis, thiab lawv cov derivatives, feem ntau muaj octanoic acid (C8H6O2) thiab decanoic acid (C0H20O2). MCFA muaj nyob rau hauv daim ntawv ntawm triglycerides, hu ua MCT, nyob rau hauv cov zaub mov. Piv txwv li, txiv maj phaub roj muaj kwv yees li 14% thiab cov roj txiv maj phaub muaj kwv yees li7% MCT, thaum nyuj cov mis nyuj thiab mis nyuj muaj 1%-3%.
Lub cev muaj zog ntawm MCT
MCT tsuas muaj cov roj saturated fatty acids, muaj cov ntsiab lus melting tsawg, zoo stability, thiab tsis yooj yim oxidized. MCT yog cov kua dej tsis muaj xim, tsis muaj ntxhiab tsw thiab sib haum nrog ntau yam kuab tshuaj, roj, antioxidants xws li butylated hydroxytoluene, thiab cov vitamins muaj roj. Nws muaj viscosity uas yog ib nrab ntawm cov roj zaub tsis tu ncua, ua rau nws nthuav dav thiab lubricating.
Vim nws cov pa taws tsawg thiab nyiam ua npuas ncauj, MCT tsis haum ua cov roj ua noj. Los ntawm enzymatic esterification technology, nruab nrab-chain fatty acids (MCFA) thiab ntev-chain fatty acids (LCFA) tuaj yeem ua ke los tsim cov kab nruab nrab ntev-ntev triglycerides (MLCT), uas yog hom tshiab ntawm cov roj noj qab haus huv.
Cov yam ntxwv ntawm metabolic ntawm MCT
Piv rau cov saw ntev triglycerides, MCT yog yooj yim dua zom thiab nqus. MCT muaj tsawg dua nyob ntawm cov kua tsib ntsev thiab pancreatic enzymes thiab tau yooj yim hydrolyzed nyob rau hauv cov hnyuv. Nws cov khoom siv hydrolysis, MCFA, muaj cov saw hlau luv dua thiab yooj yim nqus. Tom qab nqus tau, MCFA khi nrog albumin thiab xa ncaj qha mus rau lub siab los ntawm cov hlab ntsha portal yam tsis tsim chylomicrons. MCFA koom nrog hauv cov khoom siv peripheral. Tsis tas li ntawd, MCFA tuaj yeem nkag mus rau hepatocytes 'mitochondria rau -oxidation yam tsis muaj kev cia siab rau carnitine, ua rau oxidation sai thiab ua tiav yam tsis muaj kev cuam tshuam loj hauv adipose thiab daim siab cov ntaub so ntswg. MCFA tuaj yeem txhawb nqa qhov tso tawm ntawm cholecystokinin, thaum lub zais ntawm cov kua tsib phospholipids thiab cov roj (cholesterol) qis dua piv rau cov saw ntev fatty acids. Hauv cov neeg mob pancreatic lipase lossis cov kua tsib ntsev tsis txaus, MCFA tseem tuaj yeem nqus tau, thaum cov saw hlau ntev tsis tuaj yeem nqus tau.
Cov teebmeem ntawm MCT ntawm Protein Metabolism
Experiments have shown that enteral nutrition formulations containing MCT/LCT can effectively reduce protein breakdown in patients with cerebral vascular accidents who cannot eat due to consciousness disorders, improve serum protein levels, and thus improve their nutritional status. In burn patients with a total burn area >30%, cov khoom noj khoom haus nkag mus uas muaj MCT / LCT tuaj yeem txo cov protein ntau tom qab hlawv, ua kom cov protein ntau hauv cov ntshav, thiab txhim kho cov khoom noj khoom haus ntawm cov neeg mob hlawv.
Kev cuam tshuam ntawm MCT ntawm carbohydrate metabolism
Qee cov kev tshawb fawb qhia tias MCT muaj kev tiv thaiv kab mob ntshav qab zib.MCTtuaj yeem txo qis cov rog hauv lub cev thiab txhim kho cov ntaub so ntswg thiab lub cev tiv thaiv insulin. Cov kev tshawb fawb tsiaj tau pom tias kev txhim kho cov piam thaj metabolism los ntawm MCT cuam tshuam nrog kev nce qib ntawm adiponectin. Kev nce adiponectin tuaj yeem txhim kho cov tshuaj insulin los ntawm kev ua kom cov insulin receptor substrates (IRS-1) ntsig txog phosphatidylinositol-3-kinase, AMP-activated protein kinase, thiab peroxisome proliferator-activated receptor alpha (PPAR-), thiab lwm yam. . Yog li ntawd, qee cov neeg ntseeg tias MCT ua raws li tus inducer ntawm adiponectin. Kev tshawb fawb tau pom tias kev noj MCT mus sij hawm ntev (18g ib hnub rau 90 hnub) los ntawm cov neeg mob ntshav qab zib hom 2 uas rog rog tuaj yeem txo lub cev hnyav, lub duav ncig, thiab txhim kho insulin rhiab heev. Tsis tas li ntawd, cov kev tshawb fawb tau pom tias MCT tuaj yeem txhim kho kev txawj ntse hauv cov neeg mob uas mob ntshav qab zib hom 1 hauv ntshav qab zib hom 1.
Cov teebmeem ntawm MCT ntawm lipid metabolism
Cov kev tshawb fawb tau qhia tiasMCTtuaj yeem ua kom muaj roj oxidation, txo cov rog hauv lub cev, thiab txo cov ntshav lipid. Nyob rau hauv ib txoj kev tshawb no uas muaj 23 tus txiv neej rog rog, lawv tau random muab rau cov khoom noj uas muaj roj ntau uas muaj cov txheej txheem nruab nrab-chain triglycerides (MLCT) lossis roj txiv roj. Kev siv hluav taws xob thiab lub cev muaj pes tsawg leeg tau ntsuas los ntawm kev ntsuas tsis ncaj calorimetry thiab magnetic resonance imaging. Txoj kev tshawb nrhiav pom tias MLCT tuaj yeem ua rau cov roj oxidation luv luv, tab sis nws tsis tuaj yeem tswj lub cev qhov hnyav lossis rog dhau los ntawm kev siv hluav taws xob. Hauv lwm txoj kev tshawb fawb, yim tus poj niam noj qab haus huv premenopausal noj cov zaub mov muaj roj ntau uas muaj MCT siab rau ib lub lis piam, ua raws li lwm lub lis piam noj cov zaub mov muaj roj ntau uas tsuas muaj cov kab ntev triglycerides (LCT) raws li kev tswj tus kheej. So kom txaus metabolic tus nqi thiab postprandial zog siv tau ntsuas nyob rau hnub 1 thiab Hnub 7 ntawm txhua qhov kev sim noj. Nws tau pom tias cov roj oxidation tau nce ntxiv hauv pawg MCT ntawm 5.5 teev tom qab noj mov hnub 1 thiab Hnub 7. Qhov kev sim pom tau tias kev noj MCT ua rau cov rog metabolism hauv cov poj niam noj qab haus huv, tab sis so metabolic tus nqi thiab nruab nrab lub zog postprandial. kev siv nyiaj tsis hloov.
Cov qauv triglycerides uas muaj cov roj ntsha nruab nrab thiab cov linoleic acid tuaj yeem hloov pauv qhov tshem tawm ntawm cov lipids hauv cov nas. Kev noj MCT tuaj yeem txo lub cev hnyav, lub cev rog, lub siab hnyav, qhov ntim dawb adipocyte, thiab cov ntshav triglyceride ntau ntau hauv C57BL / 6J cov nas noj cov zaub mov muaj roj ntau. Hauv ob lub sijhawm ntev thiab lub sijhawm luv luv, MCT tuaj yeem txhim kho cov ntshav thiab lub siab lipid protein ntau hauv cov nas.
HSF Biotech MCT Roj/Powder
HSF yog ib lub chaw muag khoom ntawm MCT roj thiab tshwj xeeb hauv kev ua nws rau hauv MCT hmoov. MCT hmoov no tau txais koob meej thiab tau siv dav los ntawm ntau lub tuam txhab lag luam, nrog rau hauv cov khoom noj tshwj xeeb.
MCT hmoov uas tsim los ntawm HSF muaj nyob rau hauv ntau formulations kom haum rau ntau yam kev xav tau kev noj haus. Ib qho kev tsim qauv yog kev xaiv neeg tsis noj nqaij, uas siv cov khoom xyaw cog xws li Arabica cov pos hniav ua tus nqa khoom. Cov qauv no ua kom ntseeg tau tias cov neeg ua raws li cov neeg tsis noj nqaij lossis vegan txoj kev ua neej tuaj yeem txaus siab rau cov txiaj ntsig ntawm MCT roj.
Lwm txoj kev tsim cov hmoov txhuv nplej siab ua cov khoom thauj rau MCT hmoov. Cov hmoov txhuv nplej siab yog cov khoom siv feem ntau uas ua kom yooj yim dissolvability thiab txhim khu kev ntxhib los mos ntawm cov khoom kawg. Cov qauv no tsim nyog rau ntau yam kev siv thiab muab ntau yam kev xaiv rau cov tuam ntxhab.
Tsis tas li ntawd, HSF muab cov qauv thib peb uas suav nrog casein protein ua tus nqa khoom rau MCT hmoov. Qhov kev xaiv no muaj txiaj ntsig tshwj xeeb rau cov khoom noj kho mob tshwj xeeb uas xav tau cov txiaj ntsig ntawm MCT roj nrog rau cov khoom noj khoom haus ntawm casein protein.
HSFBiotechmuab MCT roj thiab muaj ntau yam formulations ntawm MCT hmoovkom ua raws li kev nyiam noj zaub mov txawv thiab kev siv. MCT hmoov no tau txais kev siv dav ntawm cov tuam txhab lag luam thiab hauv cov khoom noj kho mob tshwj xeeb vim nws cov txiaj ntsig kev noj qab haus huv thiab ntau yam.
Xav tau cov qauv dawb, thov hu rau peb cov kws tshaj lij ntawmsales@healthfulbio.com.