L-arginineyog ib qho tseem ceeb tsis yog - amino acid, uas tsis tsuas yog koom nrog hauv cov metabolism hauv cov ntaub so ntswg hauv lub cev, tab sis kuj tseem cuam tshuam nrog cov protein metabolism thiab kev tiv thaiv kab mob hauv lub cev.
Arginine is used as an immune nutrient in physiological state, and the arginine synthesized by the body itself can meet the metabolic needs. However, in the state of stress, trauma or rapid growth, the body's demand for arginine greatly increases, and its own synthesis cannot meet the needs of physiological metabolism, so it must be replenished in time. Therefore, arginine is defined as a conditionally essential amino acid or a semi-essential amino acid.
Ntxiv nrog rau cov khoom noj khoom haus ntawm cov amino acids dav dav, arginine kuj tseem ua haujlwm ua ntej ntawm lub teeb liab molecule (nitric oxide, NO) hauv lub cev, thiab muab ntau yam tseem ceeb hauv kev ua haujlwm lom neeg. Nws ua lub luag haujlwm tseem ceeb hauv kev saib xyuas lub cev tsis muaj zog thaum lub sijhawm ua haujlwm.
Endogenous synthesis ntawm arginine
Arginine tuaj yeem tsim los ntawm glutamine (Gln) thiab proline (Pro), thiab ntshav citrulline thiab ornithine hauv mitochondria yog cov ua ntej rau arginine synthesis. Feem ntau ntawm cov enzymes koom nrog arginine synthesis tau nthuav dav hauv cov ntaub so ntswg, tab sis qee cov enzymes tseem ceeb, xws li carbamoyl phosphate synthase-1 (CPS-1), ornithine carbamoyltransferase (I degree), N monoacetylglutamate synthase (NAG), Tsuas yog txwv rau cov daim siab thiab lub plab hnyuv mucosa.
Cov nyhuv ntawm arginine ntawm kev tiv thaiv kab mob
Ntau qhov kev tshawb fawb soj ntsuam tau pom tias arginine tuaj yeem txhim kho kev tiv thaiv kab mob ntawm tib neeg lub cev. Qee cov kws tshawb fawb tau kawm txog cov txiaj ntsig ntawm arginine ntawm kev tiv thaiv kab mob qog noj ntshav thaum lub sijhawm phais, thiab pom tias arginine tuaj yeem ua kom cov lymphocyte suav, CD4 cell suav, CD4 / CD8 piv, thiab kev ua haujlwm ntawm lub hlwb tua neeg (NK) tau zoo dua. Cov txiaj ntsig kev tshawb fawb tseem ceeb hauv tsev thiab txawv teb chaws tau pom tias arginine supplementation nyob rau hauv ntau txoj kev tau pom los txhim kho kev tiv thaiv kab mob thaum kev tiv thaiv kab mob los ntawm kev phais mob, kub hnyiab, kev nyuaj siab thiab lwm yam mob.