1. Cov Khoom Taw Qhia
Hsf's Pytosterol, lossisTsob Nroj Sterol Hmoov yog hom dawb lossis yuav luag dawb hmoov extracted los ntawm taum roj distillate. Nws yog cov phytosterols nrog ntau cov lus tshwj xeeb thiab siv hauv ntau cov khoom lag luam ntawm cov roj nyoos los ntawm cov khoom siv hsf. Xyoo 2021, HSF Biotech tau coj ua cov hmoov txhuas uas tau txais daim ntawv pov thawj CGMP rau phytosterols hauv kev lag luam.
1.1 Dab tsi yog tsob ntoo sterols?
Nws tseem muaj lub npe hu ua phytososterols, ib hom steroid, uas tau dav faib hauv lub ntiaj teb biological. Pytososterols yog cov chaw ua haujlwm muaj txiaj ntsig, suav nrog -sitosterol, stigmasterol, stigmasterol, brassicasterol, brassesterol, chaw pw hav zoov, thiab lwm yam.
1.2 Cov Qauv Tshuaj Lom thiab Ua Cas Thiaj
Phytososterols txhua tus muaj cyclotomentane polyhydrophenanthrene raws li cov qauv yooj yim thiab muaj pawg cawv. Lawv tau muab faib ua -sitosterol, stigmasterol, brassicasterol thiab chaw pw hav zoov los ntawm kev sib tw sib txawv.
|
Cas Tsis tau. |
Cov Qauv Tshuaj |
|
-Saib cov papasterol, {1}}}}, 414.72 Stigmasterol, 83-48-7}}, 412.67 Chaw pw hav zoov, 474-62-4}, 400.69 Brassicicasterol, 474-67-9, 398. |
|
1.3 lub cev thiab tshuaj lom neeg
|
Khoom Snapshot |
||
|
Lub hauv paus |
DD Roj (Soy) |
Cov roj siab (ntoo thuv) |
|
Kev qhia tshwj xeeb |
95% |
98% |
|
Tus ntxhiab |
Tus yam ntxwvc |
|
|
Saj |
Me ntsis rau tsis muaj |
|
|
Kev tshwm sim |
Dawb lossis yuav luag dawb hmoov |
|
|
Tus txheeb ze ceev |
Ib nyuag loj dua li dej |
|
|
So |
Insoluble hauv dej, kua qaub thiab alkali Soluble hauv chloroform, ether, benzene, ethyl acetate Tsawg dua soluble hauv ethanol thiab acetone |
|
2. Flow daim ntawv
Pytosterol(Noj cov khoom ua kom zoo li ib qho piv txwv) yog npaj los ntawm Esterification, cov dej nag txias, recrystallization thiab cov roj ntim khoom siv siab roj.
3. Cov Qauv Zoo
|
Kev ntsuas kev lag luam zoo |
||
|
Tus Nqi Acid |
Tsawg dua los yog sib npaug rau 3mg koh / g |
|
|
Peroxide tus nqi |
Tsawg dua li lossis sib npaug rau 1 0}. 0MEQ / KG |
|
|
Poob rau ziab |
Tsawg dua los yog sib npaug rau 3% |
|
|
Residue ntawm ignition |
Tsawg dua los yog sib npaug rau 1% |
|
|
Lam xav |
||
|
Cov ntsiab lus ntawm phytosterol |
Ntau dua los yog sib npaug rau 95% (soy tau los) |
Ntau dua los yog sib npaug rau 98% (ntoo thuv) |
|
Beta-sitosterol |
Ntau dua los yog sib npaug rau 30% |
Ntau dua los yog sib npaug rau 70% |
|
Tooj dag |
Tsawg dua los yog sib npaug rau 10% |
Tsawg dua los yog sib npaug rau 0. 5% |
|
Tus muaj stigmasterol |
Ntau dua los yog sib npaug rau 12% |
Tsawg dua los yog sib npaug rau 1.5% |
|
Pem teb |
Ntau dua los yog sib npaug rau 15% |
Tsawg dua los yog sib npaug rau 15% |
|
Lwm yam sterols |
Tsawg dua los yog sib npaug rau 10% |
Tsawg dua los yog sib npaug rau 10% |
|
Yuav |
||
|
Txhuas (PB) |
Tsawg dua los yog sib npaug rau 1. 0 ppm |
|
|
Arsenic (raws li) |
Tsawg dua los yog sib npaug rau 1. 0 ppm |
|
|
Cadmium (CD) |
Tsawg dua los yog sib npaug rau 1. 0 ppm |
|
|
Mercury (Hg) |
Tsawg dua los yog sib npaug rau 0. 1ppm |
|
|
B(a)p |
Tsawg dua los yog sib npaug rau 2. 0 ppb |
|
|
Residual cov kuab tshuaj |
Tsawg dua los yog sib npaug rau 50ppm |
|
|
Microbiological |
||
|
Tag nrho aerobic microbial suav |
Tsawg dua li lossis sib npaug rau 1000cfu / g |
|
|
Tag nrho cov poov xab thiab pwm suav |
Tsawg dua los yog sib npaug rau 100cfu / g |
|
|
E. coli |
Qhov tsis zoo / 10g |
|
4. Lohol Series Pytosterols
HSF Biotech muaj cov ntau ntawm cov khoom zooPytosterolCov khoom lag luam. Los ntawm soy-spourcedPytosterolrau ntoo thuv-based phytosterol khoom, hsf biotech lub lowchol Cov koob tuaj yeem siv rau ntau yam khoom noj npaj ua cov rdl reducer. Vim yog lawv emulsifying thiab stabilizing tej yam, lawv kuj tseem siv tau cov tshuaj pleev ib ce.
|
Khoom npe |
Lub hauv paus |
Kev qhia tshwj xeeb |
Nta |
Lub thawv |
Daim ntawv thov |
|
Phytosterols (Psb) |
Kua yaub |
95% |
Hmoov hmoov |
25kg / hnab / nruas, lossis customized raws li thov |
Cov khoom noj muaj nuj nqi, ntsiav tshuaj, cov ntsiav tshuaj tawv |
|
Phytosterols (PSA) |
Tus ntoo |
98% |
Hmoov hmoov |
25kg / hnab / nruas, lossis customized raws li tau thov |
Nplua nuj in -sitosterol Cov khoom noj muaj nuj nqi, ntsiav tshuaj, cov ntsiav tshuaj tawv |
|
Phytosterols (G-psb) |
Kua yaub |
90% |
Tus granule |
25kg / hnab / nruas, lossis customized raws li tau thov |
Zoo heev ntws muaj peev xwm Cov khoom noj muaj nuj nqi, ntsiav tshuaj, cov ntsiav tshuaj tawv |
|
Phytosterols (P-psb) |
Kua yaub |
90% |
Hmoov hmoov |
25kg / hnab / nruas, lossis customized raws li tau thov |
Nplua nuj in -sitosterol & zoo heev ntws muaj peev xwm Cov khoom noj muaj nuj nqi, ntsiav tshuaj, cov ntsiav tshuaj tawv |
|
Tus muaj stigmasterol |
Kua yaub |
90%, 95% |
Hmoov hmoov |
25kg / hnab / nruas, lossis customized raws li tau thov |
Kev tsim kho tsob ntoo kev txhim kho, prodrugs, cov khoom siv raw ntawm cov tshuaj pleev ib ce kawg |
|
-SiSterol |
Soy / ntoo thuv |
60%, 70% |
Hmoov hmoov |
25kg / hnab / nruas, lossis customized raws li tau thov |
Nplua nuj in -sitosterol Prodrug, raw khoom ntawm high-end tshuaj pleev ib ce |
5. Muaj nuj nqi
Phytososterols feem ntau coolsist nrog roj thiab cov rog hauv cov noob cog thiab ua lub luag haujlwm tseem ceeb hauv lub koom haum cell thiab kev tsim kho cell.
6. Cov ntawv thov
3.1 Tsob Nroj Sterol HmoovSiv rau hauv cov khoom noj thiab kev lag luam kev lag luam
In 1999, the US Food and Drug Administration (FDA) approved the "healthy" label on foods fortified with phytosterols and phytosterol esters.
Hauv 2010, phytososterols thiab phytosterols tau raug tso cai rau cov zaub mov muaj kev nyab xeeb thiab kev noj qab haus huv tshiab ntawm kev noj qab haus huv ntawm cov neeg lub koom pheej ntawm Tuam Tshoj).
Cov khoom noj khoom haus cov khoom noj khoom haus, cov roj, cov khoom noj zaub, cov kua txiv, mij thiab zaub noj nqaij noj.
3.2 Thov nyob rau hauv kev lag luam kev lag luam
Cov hmoov tsob ntoo sterol yog siv los ua cov tshuaj steroid hauv kev lag luam tshuaj
3.3 daim ntawv thov hauv kev lag luam kom hniav
7. Kuaj cov khoom siv
 |
 |
| Kuaj ntsuas: Roj Chromatography |
Cov Khoom Siv Hnyav Hlau Cov Khoom Siv: Atomic nqus spectrophatometer |
8Cov. Pob & Cia
Pob:25KG Fiber nruas (zaub mov qib)
Cia:Cov khoom yuav muab khaws cia rau 24 lub hlis ntawm chav tsev kub hauv cov thawv ntim khoom qub. Nwsyuav tsum muab khaws cia rau hauv cov thawv kaw ntom nti ntawm chav sov, thiab tiv thaiv los ntawm tshav kub, lub teeb,ya raws, thiab oxygen.
9. Peb cov ntawv pov thawj ntawm Phytosterols
10. Kev nthuav qhia
Cim npe nrov: Pytosterol, Tuam Tshoj, Hoobkas, tuam ntxhab, cov chaw tsim khoom, tsim khoom, lag luam, yuav khoom, loj, zoo tshaj plaws, cia muag
