Arachidonic acid yog tam sim no nyob rau hauv tag nrho cov mammalian hlwb, feem ntau yog esterified los ua daim nyias nyias phospholipids, thiab yog ib qho ntawm feem ntau polyunsaturated fatty acids nyob rau hauv tib neeg cov ntaub so ntswg. High-purityarachidonic acid hmoovNws yog ib qho ncaj qha precursor rau kev sib txuas ntawm eicosane derivatives xws li prostaglandins, thromboxanes, thiab leukotrienes. Cov tshuaj bioactive no muaj txiaj ntsig tseem ceeb heev rau tib neeg lub plawv thiab lub cev tiv thaiv kab mob.
Arachidonic acid tuaj yeem txhawb kev sib txuas ntawm thyrotropin-tso cov tshuaj hormones hauv hypothalamus thiab txhawb kev tso tawm cov tshuaj hormones loj hlob los ntawm lub caj pas pituitary, uas muaj txiaj ntsig zoo rau kev loj hlob thiab kev loj hlob ntawm cov menyuam mos. Nyob rau tib lub sijhawm, arachidonic acid yog ib feem tseem ceeb ntawm lub retina thiab muaj nyob rau hauv daim nyias nyias phospholipids ntawm retinal hlwb, thiab retinal photoreceptor hlwb muaj ntau phospholipids, yog li arachidonic acid tuaj yeem txhawb kev loj hlob ntawm retinal photoreceptor hlwb hauv cov menyuam mos.
Arachidonic acid yog qhov ua ntej tam sim ntawm ntau cov khoom siv bioactive, eicosanoid derivatives. Cov tshuaj bioactive no muaj cov kev tswj hwm tseem ceeb ntawm cov lipid thiab protein metabolism, hemorheology, vascular elasticity, leukocyte muaj nuj nqi thiab platelet activation.
ARA yog dav faib nyob rau hauv nruab nrab rog ntawm cov tsiaj. Vim nws cov khoom siv lom neeg tshwj xeeb, arachidonic acid tau dav siv hauv cov khoom noj, tshuaj, tshuaj, tshuaj pleev ib ce thiab lwm yam lag luam, thiab nws daim ntawv thov tseem ceeb yog ib qho ntxiv hauv kev lag luam me nyuam mos. Arachidonic acid tau ntev tau pom zoo kom muab ntxiv rau cov mis mos ua cov khoom noj khoom haus ntxiv los ntawm cov tub ceev xwm thoob ntiaj teb xws li World Health Organization.
Piv nrog rau cov khoom noj khoom haus ib txwm muaj, lub cim tshiab ntawm cov menyuam mos mis mis hmoov ntxiv nrogarachidonic acidmuaj qhov zoo sib xws hauv kev txhawb nqa kev loj hlob ntawm cov menyuam mos thiab menyuam yaus. Txawm hais tias ARA tuaj yeem muab rho tawm los ntawm linoleic acid nyob rau hauv tib neeg lub cev, nws yog synthesized nyob rau hauv tsawg heev. ARA deficiency tej zaum yuav muaj kev cuam tshuam loj heev rau kev loj hlob ntawm tib neeg cov ntaub so ntswg thiab lub cev, tshwj xeeb tshaj yog kev loj hlob ntawm lub hlwb thiab lub paj hlwb.