Cov yam ntxwv ntawm liposome thev naus laus zis tau txhim kho ntau yam kev siv ntawm ntau yam khoom uas nyuaj rau yaj thiab tsis yooj yim rau khaws cia, xws liLiposomal Vitamin C. Nws txhim kho bioavailability, stability, txhim khu cov khoom haum, txo qhov tsis zoo tshwm sim. Thiab nws muaj kev kho mob zoo heev.
Liposomes feem ntau xa mus rau me me kaw vesicles nrog bilayer-encapsulated dej theem qauv tsim los ntawm dispersing lipids xws li phospholipids hauv dej. Vim tias lawv cov kab ke zoo ib yam li cov khoom siv roj ntsha, lawv tuaj yeem hu ua cov khoom siv roj ntsha. Yog li, dab tsi yog qhov zoo ntawm liposomes?
1. Ntau txoj hauv kev ntawm kev tswj hwm: Ntxiv rau txoj kev tswj hwm feem ntau los ntawm kev txhaj tshuaj, liposomes kuj tseem tsim nyog rau kev tswj hwm qhov ncauj, kev tswj xyuas qhov muag, kev tswj xyuas pulmonary inhalation, thiab kev tswj hwm kev hloov pauv.
2. Targeting: Ordinary liposomes muaj daim siab thiab tus po lub hom phiaj. Liposomes tuaj yeem muaj lub hom phiaj tshwj xeeb tom qab hloov kho los ntawm monoclonal antibodies thiab lwm yam tshuaj tiv thaiv.
3. Kev ua haujlwm ntev: ntev liposomes tuaj yeem ua kom lub sijhawm khaws cia ntawm cov tshuaj hauv cov ntshav, uas muaj txiaj ntsig zoo rau kev ua kom cov tshuaj' qhov ua tau zoo.
4. Zoo histocompatibility: Liposomes muaj cov cell affinity zoo thiab histocompatibility nrog cov qauv zoo ib yam li cov kab mob lom. Nws tuaj yeem raug adsorbed ib ncig ntawm lub hom phiaj rau lub sijhawm ntev thiab ncaj qha nkag mus rau cov hlwb los ntawm lysosomes. Kev zom cov tshuaj tso tawm.
5. Txo cov tshuaj toxicity: Tom qab liposomes encapsulate cov tshuaj, cov nyiaj cumulative nyob rau hauv lub plawv thiab lub raum yog qis dua li ntawm cov tshuaj dawb. Yog li, cov tshuaj uas muaj tshuaj lom rau lub plawv thiab lub raum tuaj yeem npaj rau hauv liposomes kom txo cov tshuaj toxicity.
6. Kev ruaj ntseg tshuaj: Qee cov tshuaj txaus ntshai hauv ib puag ncig tshwj xeeb tuaj yeem tiv thaiv los ntawm liposome bilayer los txhim kho lub zog ntawm qee cov tshuaj.
Covliposomal vitamin Cnpaj los ntawm HSF yog raws li cov yam ntxwv ntawm liposomes los txhim kho kev ruaj ntseg ntawm VC thiab tau siv rau ntawm qhov loj. Nws tau ua lub luag haujlwm zoo dua hauv kev txhawb nqa tib neeg kev noj qab haus huv.