Cog sterols, tseem hu ua phytosterols, yog ib hom steroid compound uas muaj dav hauv zaub, txiv hmab txiv ntoo, legumes, txiv ntseej, nplej, thiab lwm yam nroj tsuag. Lawv muaj cov haujlwm zoo xws li txo cov roj cholesterol, antioxidant, tiv thaiv kab mob, inhibiting kev loj hlob ntawm cov qog nqaij hlav cancer, kho cov tawv nqaij barrier, thiab soothing tawv nqaij, thiab feem ntau yog siv rau hauv cov zaub mov noj, tshuaj pleev ib ce, tshuaj, kev ua liaj ua teb, thiab tsiaj txhu. Txawm li cas los xij, cov nroj tsuag sterols tsis zoo soluble hauv dej thiab roj, zoo heev txwv lawv daim ntawv thov. Yog li ntawd, cov kws tshawb fawb feem ntau xaiv los ua ke cog sterol esters uas muaj ntau dua soluble hauv cov roj theem ua ntej siv lawv.
Ob txoj hauv kev tseem ceeb rau kev tsim cov nroj tsuag sterol esters
Tam sim no, muaj ob txoj hauv kev tseem ceeb rau kev sib txuas cov nroj tsuag sterol esters: tshuaj synthesis thiab enzyme-catalyzed synthesis.
Kev siv tshuaj lom neeg suav nrog kev siv tshuaj lom neeg los tsim cov ester bond ntawm cov nroj tsuag sterol thiab ib qho cawv molecule. Txoj kev no yuav tsum tau siv cov kuab tshuaj lom neeg cov kuab tshuaj, thiab cov tshuaj tiv thaiv yuav tsum tau ua tib zoo tswj kom tsis txhob muaj kev xav sab nraud. Tshuaj synthesis yog ib tug complex thiab kim txheej txheem, thiab tej zaum yuav tshwm sim nyob rau hauv tsim ntawm undesired byproducts uas yuav cuam tshuam rau purity thiab zoo ntawm cov khoom kawg.
Enzyme-catalyzed synthesis suav nrog kev siv cov enzymes, xws li lipases, los ua kom cov tshuaj tiv thaiv esterification ntawm cov nroj tsuag sterol thiab ib qho cawv molecule. Txoj kev no suav hais tias yog ib puag ncig zoo thiab muaj txiaj ntsig ntau dua li cov tshuaj synthesis. Enzyme-catalyzed synthesis tso cai rau kev tswj hwm ntau dua ntawm cov tshuaj tiv thaiv kab mob thiab tuaj yeem tsim cov txiaj ntsig siab dua ntawm cov nroj tsuag ntshiab sterol esters. Txawm li cas los xij, tus nqi ntawm kev siv cov enzymes tuaj yeem siab, thiab lub sijhawm tshuaj tiv thaiv yuav ntev dua piv rau cov tshuaj synthesis. Hauv cov ntsiab lus, ob qho tib si tshuaj synthesis thiab enzyme-catalyzed synthesis muaj qhov zoo thiab qhov tsis zoo nyob rau hauv kev sib xyaw ntawm cov nroj tsuag sterol esters, thiab kev xaiv ntawm txoj kev yog nyob ntawm qhov xav tau cov khoom zoo, yield, thiab cov nqi txiav txim siab.
Plant Sterols (esters) cov yam ntxwv
Cog sterols (esters) muaj cov yam ntxwv tshwj xeeb uas paub qhov txawv ntawm lwm cov biomolecules. Lawv yog tsim los ntawm plaub lub nplhaib, hu ua steroid nucleus, uas yog tsim los ntawm peb lub nplhaib cyclohexane thiab ib lub nplhaib cyclopentane. Txoj hauj lwm ntawm methyl thiab ethyl pawg ntawm cov nplhaib sib txawv ntawm cov roj cholesterol, uas yog lub ntsiab sterol pom hauv cov ntaub so ntswg tsiaj. Vim hais tias ntawm lawv cov qauv, cov sterols cog (esters) muaj cov txheej txheem siab rigidity, uas ua rau lawv resistant rau ob qho tib si enzymatic thiab tshuaj degradation.
Tsis tas li ntawd, cov nroj tsuag sterols (esters) muaj ib pab pawg hydroxyl ntawm txoj haujlwm C3, thiab qee qhov kuj muaj ob daim ntawv cog lus ntawm txoj haujlwm C5 thiab / lossis C7. Cov yam ntxwv ntawm cov qauv no ua lub luag haujlwm tseem ceeb hauv kev ua haujlwm lom neeg ntawm cov nroj tsuag sterols (esters) thiab lawv cov txiaj ntsig zoo rau tib neeg kev noj qab haus huv.
Cog sterol esters yog cov khoom xyaw nrov hauv cov tshuaj pleev ib ce thiab cov khoom tu tawv nqaij
1. Siv rau hauv kev tu tawv nqaij, cog sterols (esters) muaj txiaj ntsig zoo rau kev noj qab haus huv ntawm daim tawv nqaij. Lawv tuaj yeem cuam tshuam cov tawv nqaij o, kho cov tawv nqaij barrier, alleviate daim tawv nqaij khaus, kho cov tawv nqaij rhiab heev, retard daim tawv nqaij laus, txhim kho daim tawv nqaij elasticity, thiab txo cov tawv nqaij roughness. Lub mechanism ntawm kev kho cov tawv nqaij barrier muaj nuj nqi yog raws li nram no: lub cell membrane muaj phospholipids, glycolipids, sterols, thiab ib co proteins. Thaum cov ntsiab lus sterol hauv cov cell membrane ntau dua 10 feem pua, sphingolipids thiab sterols cuam tshuam nrog cov protein thiab lipids los tsim cov lipid raft qauv. Lipid rafts cuam tshuam rau membrane stability, membrane fluidity, thiab membrane protein thauj, thiab lwm yam dej num. Cog sterols tuaj yeem pauv txoj haujlwm nrog cortisol, hloov nws, lossis ntxiv qhov chaw seem uas tsim los ntawm kev poob ntawm lub cev, yog li rov ua kom cov tawv nqaij ruaj khov.
2. Siv rau hauv kev tu plaub hau, ntxiv cov nroj tsuag sterols rau cov tshuaj zawv plaub hau thiab cov cua txias tuaj yeem muab cov plaub hau muag muag thiab ci iab, txo qhov dryness, thiab tiv thaiv cov plaub hau poob. Txawm hais tias tsis muaj kev tshawb fawb ntau txog kev tiv thaiv plaub hau los ntawm cov nroj tsuag sterols, muaj peev xwm theoretical rau lawv los tiv thaiv cov plaub hau. Cov kev xav hauv qab no yog raws li hauv qab no: Muaj ntau yam uas tuaj yeem ua rau cov plaub hau poob, xws li androgens, hloov pauv kev loj hlob ntawm TGF- 2, prostaglandin D2, thiab lwm yam. Qhov tseem ceeb tshaj plaws yog androgens, uas yog hloov los ntawm cov roj cholesterol los ntawm enzymes. . Testosterone hloov los ntawm 5 -reductase rau hauv dihydrotestosterone (DHT), uas paub tias ua rau cov plaub hau poob los ntawm ntau yam txheej txheem.
Ua ntej, DHT khi rau androgen receptors thiab cuam tshuam cov txheej txheem hloov pauv. Qhov thib ob, DHT upregulates cov synthesis ntawm TGF - 2 nyob rau hauv lub dermal papilla, uas induces lub synthesis thiab activation ntawm caspase, ua rau cell apoptosis thiab ua rau ib tug ua ntej catagen theem thiab ib tug luv luv anagen theem. Thib peb, kev khi ntawm DHT rau androgen receptors cuam tshuam nrog Wnt / -catenin txoj hauv kev, cuam tshuam kev tso tawm ntawm cov plaub hau kev loj hlob zoo xws li Wnt10b thiab tso cov kab mob tiv thaiv kab mob xws li interleukin-6, cuam tshuam rau kev loj hlob thiab kev sib txuas lus ntawm keratinocytes thiab fibroblasts nyob ib ncig ntawm cov hauv paus plaub hau.
Cov sterols cog tuaj yeem txo cov roj cholesterol thiab mob, thiab txhawb kev loj hlob ntawm fibroblasts nyob ib ncig ntawm cov hauv paus plaub hau. Cov yam tseem ceeb no muab theoretical possibilities rau kev tiv thaiv ntawm cov plaub hau poob los ntawm cov nroj tsuag sterols.
3. Siv rau hauv cov khoom siv tshuaj pleev ib ce. Cog sterols thiab lawv cov esters tuaj yeem txhim kho kev ntxhib los mos thiab ci. Lawv feem ntau siv hauv tshuaj pleev ib ce xws li lipsticks, hmoov, thiab mascaras.
HSF Biotech cog sterol (esters)
Lub Cosmetic Ingredient Review (CIR) tau tshaj tawm txog 26 cov nroj tsuag sterols thiab cog sterol esters uas tuaj yeem siv rau hauv cov tshuaj pleev ib ce. Cov khoom xyaw no yog siv los ua cov tshuaj pleev tawv nqaij, cov plaub hau txias, cov tshuaj viscosity, tshuaj tiv thaiv tawv nqaij, antioxidants, preservatives, thiab fragrances hauv tshuaj pleev ib ce. Txawm li cas los xij, cov tebchaw no nthuav tawm tsis zoo solubility thiab muaj lub siab melting point, uas txwv lawv cov khoom muaj roj ntsha thiab siv tau. Yog li ntawd, HSF Biotech Lub Tuam Txhab ntau yam kev hloov kho lub cev thiab tshuaj lom neeg tau tsim los txhim kho lawv cov khoom, nrog esterification yog txoj kev siv ntau tshaj plaws.
HSF Biotech txaus siab los tsim cov nroj tsuag zoo sterols (esters) thiab microencapsulated hmoov uas muaj ntau yam kev siv hauv ntau yam lag luam. Peb cov khoom cog sterol (ester) tau siv dav hauv cov khoom noj, tshuaj pleev ib ce, thiab tshuaj lag luam ua cov khoom xyaw ua haujlwm, vim lawv cov roj (cholesterol) txo qis, tiv thaiv kab mob, thiab antioxidant zog.
Tau ntau xyoo, HSF Biotech tau tsim kev koom tes nrog cov tuam txhab ua lag luam hauv cov khoom noj, kev zoo nkauj, thiab kev noj qab haus huv, muab lawv cov khoom lag luam zoo thiab zoo cog sterol (ester) kom tau raws li lawv cov kev xav tau tshwj xeeb.
Tsis tas li ntawd, HSF lub tuam txhab tau ua qhov tseem ceeb hauv kev txhim kho microencapsulated cog sterol (ester) hmoov. Cov thev naus laus zis tshiab no suav nrog cov khoom cog sterols (esters) hauv cov txheej tiv thaiv, uas txhim kho lawv txoj kev ruaj ntseg, solubility, bioavailability, thiab functionality.
Tsis tas li ntawd, lawv muaj cov ntawv thov ua cov khoom xyaw ua haujlwm hauv cov khoom tu tus kheej, xws li cream, tshuaj pleev, thiab tshuaj zawv plaub hau.
HSF Biotech zoo siab rau kev nthuav dav ntawm peb cov nroj tsuag sterol (ester) thiab microencapsulated hmoov cov khoom, thiab peb tau cog lus tias yuav txuas ntxiv mus tsim thiab tsim cov thev naus laus zis tshiab uas yuav ua rau muaj kev siv dav dua rau cov khoom tseem ceeb no.
Xav tau cov qauv dawb, thov hu rau peb cov kws tshaj lij ntawmsales@healthfulbio.com.