Cov kws tshawb fawb tau tsom mus ntev rau txoj kev tshawb fawb thiab kev siv cov khoom noj khoom haus, ua tiav kev nce qib tseem ceeb. Xyoo 1905, Lavxias kws tshawb fawb Gulewitsch thiab Kvimberg thawj zaug rho tawm carnitine los ntawm cov leeg. Cov qauv tshuaj ntawm carnitine tau txiav txim siab hauv xyoo 1927, qhia tias nws muaj ob isomers:L-carnitine yog sivthiab D-carnitine. Kev tshawb fawb tau pom tias tsuas yog L-carnitine muaj txiaj ntsig zoo rau tsiaj. Xyoo 1985, Chicago International Nutrition Conference tau lees paub L-carnitine ua ib qho khoom noj tseem ceeb hauv cov xwm txheej tshwj xeeb. Kev tshawb fawb ntxiv tau qhia tias kev ntxiv L-carnitine tuaj yeem txhim kho kev qaug zog thiab txhim kho kev ua kis las.
L-carnitine thiab nws cov haujlwm
- Cov qauv tshuaj ntawm L-carnitine
L-carnitine, tseem hu ua carnitine lossis vitamin BT, muaj cov tshuaj npe B-hydroxy-Y-trimethylaminobutyric acid. Nws cov mis molecular yog C7H15NO3, thiab nws yog dawb crystalline los yog pob tshab hmoov. Nws muaj qhov hnyav molecular ntawm 161.2 thiab yooj yim soluble hauv dej thiab ethanol. L-carnitine nthuav tawm kev ruaj ntseg zoo tab sis nws yooj yim rau hygroscopicity.
- Cov ntaub ntawv ntawm L-carnitine supplementation
Feem ntau, L-carnitine cia rau hauv cov txiv neej laus yog li ntawm 20-25g, nrog 95% ntawm nws muaj nyob rau hauv cov leeg pob txha. Kev txhawb nqa L-carnitine tuaj yeem ua kom cov ntshav tsis muaj L-carnitine thiab cov leeg nqaij carnitine. Hauv kev soj ntsuam kev tshawb fawb txog tib neeg, qhov ntau npaum li cas ntawm L-carnitine supplementation feem ntau yog nyob ntawm 1 mus rau 4g, tab sis qhov kev pom zoo thiab lub sijhawm ntawm kev noj haus tseem tsis tau meej.
Vim tias muaj cov tshuaj lom neeg muaj txiaj ntsig ntawm L-carnitine thiab nws qhov kev cuam tshuam rau kev degradation, ib daim ntawv ruaj khov hu ua L-carnitine tartrate feem ntau yog siv los hloov L-carnitine hauv kev sim thiab chaw kho mob. Lwm cov ntaub ntawv ntxiv suav nrog nws cov ntawv esterified xws li acetyl-L-carnitine, propionyl-L-carnitine, thiab Glycine Propionyl-L-Carnitine (GPLC). Ntawm lawv, GPLC yog ib hom nqaij leeg tshwj xeeb ntawm carnitine uas txhim kho endothelial muaj nuj nqi thiab txhawb kev siv ntau tshaj plaws ntawm cov leeg nqaij. Tsis tas li ntawd, kev noj zaub mov ntau-carbohydrate lossis insulin tuaj yeem ua rau muaj kev nthuav qhia carnitine thauj protein (OCTN) mRNA, yog li ua kom cov carnitine nce hauv cov leeg pob txha.
Cov nyhuv ntawm kev tawm dag zog ntawm L-carnitine
Ntau qhov kev tshawb fawb tau pom tias kev cob qhia kev tawm dag zog muaj kev cuam tshuam me ntsis rau tag nrho L-carnitine. Feem ntau, plasma-dawb carnitine qib txo qis, thaum cov nqaij carnitine cov ntsiab lus nce. Kev tshawb fawb tau pom tias cov ntshav plasma L-carnitine qis dua hauv cov neeg ncaws pob uas tau kawm tsis tu ncua piv rau cov pej xeem. Kev tawm dag zog tuaj yeem ua rau muaj kev tso tawm ntawm L-carnitine los ntawm 55mg / d mus rau 94mg / d, feem ntau hauv daim ntawv ntawm acylcarnitine, qhia txog qhov xav tau L-carnitine supplementation ua ntej thiab tom qab kev tawm dag zog siab. Txawm li cas los xij, cov neeg tau txais kev cob qhia muaj peev xwm ntau dua los tuav cov carnitine dawb thaum lub sij hawm ua haujlwm hnyav piv rau cov neeg tsis tau kawm.
Qhov cuam tshuam ntawm L-carnitine supplementation ntawm kev ua kis las
Muaj cov ntawv ceeb toom qhia tias cov neeg mob uas tsis muaj carnitine muaj kev cuam tshuam ntau dhau ntawm lipid hauv cov leeg pob txha, tshwj xeeb tshaj yog nyob rau hauv hom I nqaij fibers. Tom qab kev tawm dag zog, muaj qhov txawv txav ntawm cov ntshav lactate concentration, nce lactate / pyruvate piv, thiab cuam tshuam mitochondrial respiratory chain function. Txawm li cas los xij, feem ntau pom tau hais tias nyob rau hauv ib txwm muaj mob, tsis tas yuav tsum tau ntxiv cov tshuaj carnitine ntau ntxiv. Txawm li cas los xij, ntxiv qee qhov koob tshuaj carnitine thaum lub sijhawm ua haujlwm nruab nrab siv zog tuaj yeem ncua kev qaug zog thiab txhim kho ob qho tib si aerobic thiab anaerobic muaj peev xwm. Cov kev tshawb fawb tau pom tias L-carnitine supplementation yog ib txoj kev mus sij hawm ntev, thiab ib zaug ntxiv ntawm L-carnitine ua ntej kev tawm dag zog tsis muaj kev cuam tshuam rau kev ua kis las.
- Qhov cuam tshuam ntawm L-carnitine supplementation ntawm aerobic muaj peev xwm
Nyob rau hauv xyoo tas los no, ntau qhov kev tshawb fawb tau pom tias ntxiv L-carnitine tuaj yeem txhim kho lub peev xwm aerobic nyob rau hauv cov nqe lus ntawm anaerobic threshold, siab tshaj plaws oxygen uptake, lactate clearance peev, thiab plawv ua haujlwm. Nws muaj txiaj ntsig zoo rau cov neeg ncaws pob qib siab, thiab L-carnitine supplementation tuaj yeem txhim kho kev ua kom muaj zog nyob rau hauv qis-siab thiab qis-oxygen, ua rau nws muaj feem xyuam rau kev kawm siab.
- Qhov cuam tshuam ntawm L-carnitine supplementation ntawm anaerobic muaj peev xwm
Feem ntau cov ntawv ceeb toom qhia tias ntxiv L-carnitine tuaj yeem ua rau muaj zog tso zis thaum lub sijhawm ua haujlwm anaerobic. Lub sij hawm ntev ntxiv ntawm L-carnitine tuaj yeem ua kom lub zog tso tawm los ntawm 11% thaum lub zog siv zog (80% VO2max). Kev ntxiv txhua hnub ntawm 1.5g ntawm GPLC rau 28 hnub tuaj yeem txhim kho lub zog siab tshaj plaws thaum lub sijhawm ua haujlwm los ntawm 3% mus rau 6%.
HSF Biotech SoliPro™ Micro-Encapsulated Khoom Powder L-carnitine
L-carnitine, tseem hu ua levocarnitine, yog lub ntuj sib xyaw uas ua lub luag haujlwm tseem ceeb hauv cov metabolism hauv lub zog. Nws pab thauj cov roj fatty acids mus rau hauv mitochondria, uas lawv tuaj yeem hloov mus rau hauv lub zog siv tau. Cov txheej txheem no txhim kho lub cev lub peev xwm los hlawv roj rau roj, thaum kawg txhim kho kev ua siab ntev thiab kev ua haujlwm tag nrho.HSF Lub Tuam Txhab yog cov chaw tsim khoom lag luam L-carnitine, ib qho khoom siv dav siv hauv cov dej haus ua si.
HSF Biotech Company muaj kev txaus siab rau kev tsim cov khoom zooL-carnitine yog sivhmoov,kom ntseeg tau tias nws purity thiab efficiency. Peb L-carnitine yog tsim los ntawm kev tswj xyuas nruj, ua tau raws li cov qauv kev lag luam siab tshaj plaws. HSF Biotech muaj ntau hom L-carnitine kom haum rau cov kev xav tau sib txawv.
Xaiv HSF Biotech Tuam Txhab ua koj tus khub ntseeg hauv kev tsim cov dej haus ua si nrog lub zog ntawm L-carnitine. Peb cov kws tshaj lij thiab kev cog lus rau kev ua tau zoo yuav ua kom koj lub hom phiaj sawv hauv kev lag luam los ntawm kev xa cov khoom zoo thiab kev ua tau zoo.
Xav tau cov qauv dawb, thov hu rau peb cov kws tshaj lij ntawmsales@healthfulbio.com.