Qhov chaw
DHA algal roj yog muab rho tawm los ntawm algae nroj tsuag, xws li Crypthecodinium cohnii, Schizochytrium sp., Thraustochytrium sp., thiab tshaj kaum lwm microalgae hom uas muaj DHA. Tam sim no, kev tsim cov roj DHA algal siv microalgae tau ua tiav kev lag luam hauv tsev thiab thoob ntiaj teb. Muaj peb txoj hauv kev loj hlob rau DHA-tsim microalgae: photoautotrophic (autotrophic) cultivation, heterotrophic fermentation, thiab mixotrophic cultivation, nrog rau fermentation yog cov feem ntau txoj kev.
Nyob rau hauv xyoo tas los no, muaj kev loj hlob sai nyob rau hauv lub extraction technology ntawm algal roj. Supercritical extraction ntawm algal roj yog maj hloov cov tsoos n-hexane extraction txoj kev, txhim kho kev ruaj ntseg ntawm cov khoom. Kev nce qib thiab kev siv cov tshuaj molecular distillation rau kev sib cais thiab kev siv tshuab ua kom huv tau nce qhov concentration ntawm DHA hauv microalgae DHA roj.
Kev Ntsuam Xyuas Kev Nyab Xeeb ntawm DHA Algal Roj
DHA algal roj tau txais kev saib xyuas zoo raws li qhov chaw ntawm omega -3 fatty acids, tshwj xeeb tshaj yog docosahexaenoic acid (DHA). Raws li nrog txhua yam khoom noj khoom haus, ua kom nws txoj kev nyab xeeb yog qhov tseem ceeb. Ntawm no, peb yuav tham txog kev ntsuas kev nyab xeeb ntawm DHA algal roj.
DHA algal roj, raws li cov khoom noj khoom haus, yuav raug tswj xyuas nruj hauv ntau lub tebchaws. Cov tub ceev xwm xws li Lub Chaw Tswj Xyuas Khoom Noj thiab Tshuaj (FDA) hauv Tebchaws Meskas thiab European Food Safety Authority (EFSA) hauv Tebchaws Europe tau tsim cov lus qhia thiab kev tswj xyuas kom muaj kev nyab xeeb ntawm cov khoom noj khoom haus, suav nrog DHA algal roj. Cov kev cai no suav nrog ntau yam xws li qib siab tshaj plaws ntawm cov kab mob xws li cov hlau hnyav, tshuaj tua kab, thiab cov kab mob microbial.
Txhawm rau lav qhov kev nyab xeeb ntawm DHA algal roj, kev tswj xyuas nruj nruj yog siv thoob plaws hauv cov txheej txheem tsim khoom. Qhov no suav nrog kev saib xyuas cov kev cog qoob loo ntawm microalgae, ua qhov kev sim tsis tu ncua rau cov kab mob sib kis, thiab ua raws li Kev Ua Haujlwm Zoo (GMP) thiab Kev Tshawb Fawb Txog Kev Nyab Xeeb thiab Cov Ntsiab Lus Tseem Ceeb (HACCP) cov txheej txheem. Cov kev ntsuas no pab txheeb xyuas thiab txo cov kev pheej hmoo, ua kom muaj kev nyab xeeb ntawm cov khoom kawg.
Kev tshawb fawb dav dav tau ua los ntsuas kev nyab xeeb ntawm DHA algal roj. Cov kev tshawb fawb tau tshuaj xyuas nws cov teebmeem toxicological, kev ua xua, thiab kev pheej hmoo kis mus ntev. Cov kev tshawb fawb no tau ua pov thawj tsis tu ncua kev nyab xeeb ntawm DHA algal roj ua cov khoom noj khoom haus, tsis muaj qhov cuam tshuam loj heev tshwm sim thaum noj hauv cov koob tshuaj pom zoo.
Kev soj ntsuam kev nyab xeeb ntawm DHA algal roj suav nrog ntau yam, suav nrog nws cov peev txheej thiab cov txheej txheem tsim khoom, kev tswj hwm kev tswj hwm, ntsuas kev tswj kom zoo, thiab kev tshawb fawb tshawb fawb. Nrog rau kev ua raws li cov xwm txheej no, DHA algal roj tau pom tias muaj kev nyab xeeb rau kev noj thiab muaj txiaj ntsig zoo ntawm DHA omega -3 fatty acids.
Hom Hom DHA Algal Roj Cov Khoom Siv thiab Lawv Cov Txheej Txheem Ntau Lawm
Thaum DHA algal roj siv rau hauv cov khoom noj khoom haus, feem ntau txoj hauv kev yog siv cov txheej txheem microencapsulation. Microencapsulation suav nrog kev tsim cov txheej txheem tiv thaiv ib puag ncig DHA-nplua nuj algal roj, ua rau microcapsules. Cov txheej txheem no yuav pab txo qis oxidation, txo cov ntxhiab tsw, thiab hloov cov roj los ntawm cov kua rau hauv lub xeev ruaj khov, ua kom yooj yim rau nws siv thiab khaws cia. Tam sim no, cov khoom lag luam muaj microencapsulated DHA algal roj cov khoom lag luam feem ntau yog dej-soluble, txawm tias tseem muaj cov khoom siv hydrophobic microencapsulation.
Dej-soluble microencapsulated DHA algal roj, thaum raug cov dej noo, dissolves lub capsule phab ntsa thiab tsim ib qho emulsion, nrog DHA surrounded los ntawm "kua membrane." Hom microcapsule no yog tsim los tsim cov khoom noj khoom haus xws li mis hmoov, taum hmoov, hmoov nplej, thiab cov khoom zoo sib xws.
Microencapsulation
Muaj ntau txoj hauv kev rau microencapsulation, uas tuaj yeem siv rau lipid encapsulation. Cov txheej txheem tseem ceeb muaj xws li tshuaj tsuag kom qhuav, molecular inclusion, thiab interfacial polymerization. Nyob rau hauv kev lag luam ntau lawm ntawmmicroencapsulated DHA algal roj, feem ntau siv emulsion spray drying method. Qhov no suav nrog yaj cov roj algal hauv cov khoom siv phab ntsa hydrophilic, ntxiv cov emulsifier rau homogeneous emulsification, thiab tom qab ntawd muab nws rau cov tshuaj tsuag kom qhuav. Thaum lub sij hawm cov tshuaj tsuag kom qhuav, ib-theem ziab los yog ob-theem ziab siv lub txaj fluidized tuaj yeem ua haujlwm. Cov txheej txheem emulsion tshuab ziab khaub ncaws yog cov paub tab, ua rau muaj kev sib raug zoo, dispersibility, lub neej ntev, thiab tus nqi qis. Txawm li cas los xij, nws yuav raug kev txom nyem los ntawm cov teeb meem xws li qhov tsis sib xws microcapsule particle loj.
Txoj kev sib xyaw molecular feem ntau yog siv beta-cyclodextrin nrog cov qauv tshwj xeeb molecular raws li cov khoom siv phab ntsa. Beta-cyclodextrin muaj hydrophobic sab hauv kab noj hniav thiab ib tug hydrophilic sab nrauv nto. Tom qab encapsulation, qee yam khoom qub ntawm cov roj algal, xws li tsw, yuav hloov. Txoj kev no tuaj yeem npog cov ntxhiab tsw uas tsis xav tau tab sis feem ntau muaj qis dua encapsulation efficiency.
Cov txheej txheem interfacial polymerization cuam tshuam nrog dispersing cov khoom tseem ceeb, xws li algal roj, nyob rau hauv lub aqueous theem raws li cov roj me me, tom qab ntawd ntxiv cov khoom siv phab ntsa. Los ntawm kev nplawm, cov ntaub ntawv tseem ceeb thiab cov phab ntsa tau dhau los ua cov tshuaj tiv thaiv polymerization ntawm qhov sib cuam tshuam, tsim cov yeeb yaj kiab polymer rau ntawm cov roj tee. Qhov tshwm sim ntawm cov tshuaj ntsiav phab ntsa yog nyias, tab sis nws ua rau lub cev tsis ruaj khov ntawm cov khoom thiab cov teeb meem hauv kev khaws cia, yog li cuam tshuam rau nws cov khoom lag luam.
Kev ruaj ntseg ntawm Algal Roj
Lub stability ntawm algal roj, uas muaj ntau yam unsaturated fatty acids nrog rau DHA, yog yooj yim compromised thaum ua thiab cia vim oxidation. Kev tshawb fawb pom tias kev xaiv cov ntaub ntawv phab ntsa tsim nyog, ntxiv cov tshuaj antioxidants, thiab emulsifiers, nrog rau kev ua kom zoo ntawm cov txheej txheem microencapsulation, yog qhov tseem ceeb hauv kev txhim kho nws txoj kev ruaj ntseg. Kev xaiv ntawm cov khoom siv phab ntsa yog qhov tseem ceeb rau microencapsulation thiab stability ntawm DHA algal roj. Cov khoom siv phab ntsa yuav tsum tsis yog tsuas yog muaj cov dej solubility siab xwb tab sis kuj muaj cov yeeb yaj kiab zoo, emulsifying, ziab, thiab noo noo tsis kam.
Muaj peb pawg tseem ceeb ntawm cov khoom siv phab ntsa feem ntau siv los tsim DHA algal roj.
- Thawj qeb suav nrog cov pos hniav xws li cov pos hniav arabic thiab sodium alginate.
- Cov qeb thib ob suav nrog cov hmoov txhuv nplej siab, polysaccharides, thiab lawv cov derivatives, xws li cov hmoov txhuv nplej siab, maltodextrin, thiab cyclodextrins.
- Cov qeb thib peb muaj cov proteins, xws li gelatin, casein, thiab whey protein.
Los ntawm cov txiaj ntsig kev tshawb fawb tam sim no, nws pom tias kev sib xyaw ntawm ntau cov ntaub ntawv phab ntsa ua rau muaj txiaj ntsig zoo dua.
HSF Biotech Microencapsulated hmoov ntawm DHA algal roj
Microencapsulation yog cov txheej txheem siv dav hauv cov zaub mov thiab kev lag luam ntxiv los txhim kho kev ruaj ntseg, kev ua haujlwm, thiab kev siv ntau yam ntawm cov khoom siv bioactive. Ib qho chaw tseem ceeb ntawm kev txaus siab yog kev tsim cov hmoov microencapsulated los ntawm DHA algal roj.
Kev tsim cov hmoov microencapsulated feem ntau ntsib qhov kev sib tw ntawm kev tau txais cov khoom uas muaj qhov loj me thiab cov morphology. High-pressure homogenization thev naus laus zis tau ua pov thawj tseem ceeb hauv kev daws qhov teeb meem no. HSF Biotech yog ua raws li cov emulsion uas muaj DHA algal roj rau kev kub ntxhov, cov tee me me faib tuaj yeem txo qis, ua rau cov khoom sib xws ntawm qhov loj thiab cov duab. Qhov kev sib txuam no ua kom muaj kev noj tshuaj zoo ib yam thiab txhim kho tag nrho qhov zoo ntawm cov khoom kawg.
Ib qho kev txhawj xeeb uas cuam tshuam nrog DHA algal roj yog nws cov saj txawv, uas tuaj yeem ua rau tsis zoo rau qee yam kev siv. High-pressure homogenization thev naus laus zis muab cov kev daws teeb meem zoo los ntawm kev tsim cov teeb meem nyob ib puag ncig cov roj tee, yog li tiv thaiv kev sib cuag ncaj qha nrog cov receptors. Cov txheej txheem encapsulation no zoo npog qhov saj ntawm DHA algal roj, ua rau nws palatable thiab haum rau ntau yam formulations, nrog rau cov khoom noj khoom haus, dej haus, thiab kev noj haus.
HSF Biotech kev siv cov cuab yeej siv hluav taws xob siab homogenization hauv kev tsim cov hmoov microencapsulated los ntawm DHA algal roj muaj cov txiaj ntsig zoo. Nws kov yeej cov teeb meem ntsig txog qhov tsis sib xws, ua rau muaj kev ua haujlwm ntawm lub ntsej muag, thiab nthuav tawm cov peev txheej ntawm DHA algal roj. Cov txiaj ntsig microencapsulated hmoov muab kev ruaj ntseg zoo dua, kev tuav tau yooj yim, thiab kev sib raug zoo dua, ua rau nws muaj kev xaiv zoo rau ntau yam khoom noj, dej haus, thiab cov tshuaj ntxiv. Cov thev naus laus zis no ua lub luag haujlwm tseem ceeb hauv kev ua kom tau raws li cov neeg siv khoom xav tau rau cov khoom siv tshiab, yooj yim, thiab palatable fortified nrog DHA algal roj.
Xav tau cov qauv dawb, thov hu rau peb cov kws tshaj lij ntawmsales@healthfulbio.com.